Faculty
- Dr.P.Sundaresan
- Dr.A.Vanniarajan
Clinician Scientists
- Dr.P.Vijayalakshmi
- Dr.Manoranjan Das
- Dr.R.Kim
- Dr.SR.Krishnadas
- Dr.Usha Kim
- Dr.R.Santhi
Research Scholars
- K.Renugadevi
- N.Prasanthi
- Anshuman Verma
- Sushilkumar Dubey
- G.Gowthaman
- Roopam
- Bibhuti Saikia
- Akram Husain
Senior Technicians
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MOLECULAR GENETICS
Our research focuses on identifying and characterizing the genes that are involved in various ocular disorders in Indian population. Screening Single Nucleotide Polymorphisms that could be potential risk factors for the disease condition and understanding the mutation spectrum of the genes will provide an insight into molecular diagnosis. Phenotype-Genotype correlation and gene expression studies are performed extensively to understand the mechanism of the pathogenesis. Thus the field of Molecular Genetics is evolving to encompass techniques that are directly relevant to the research and diagnosis of various eye diseases.
Ongoing Projects
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Molecular Genetics of Albinism in the Indian Population
- A genetic component to the INDEYE study of cataract and age-related macular degeneration in India
- Molecular genetics of Leber Congenital Amaurosis in South Indian population
- Mitochondrial genes involvement in Leber's Hereditary Optic Neuropathy (LHON)
- Molecular genetic analysis of candidate genes associated with paediatric eye diseases exclusively anophthalmia and microphthalmia in India
- Genetic screening in a large family with primary open angle glaucoma
- Genetic and transcript analysis of RB1 gene in South Indian retinoblastoma patients
- Transcriptome and Proteome Analysis of ALR2 gene and its involvement in the pathogenesis of Diabetic Retinopathy
Completed projects
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Genetic and Functional analysis of Fuch's Endothelial Corneal Dystrophy (FECD) and Congenital Hereditary Endothelial dystrophy (CHED) in Indian patients
- Identification of Genetic defects occurring in Indian Oculocutaneous (OCA) and Ocular Albinism (OA) families)
- Genetic and functional dissection of FOXL2 gene involved in the pathogenesis of the Blepharophimosis syndrome (BPES)
- Molecular Genetics of Keratoconus
- Screening of LOXL1 gene mutations in exfoliation glaucoma patients
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